羧甲基脫乙酰殼多糖
羧甲基脫乙酰殼多糖
CARBOXYMETHYL CHITOSAN
Cas No:83512-85-0
安心度
羧甲基脫乙酰殼多糖的醫用別名為羧甲基殼聚糖,在細胞抗炎實驗中,可以顯著降低IL6及TNFα水平,人體實驗中也體現出抗炎的作用;動物實驗促進皮膚角質層形成細胞生成,加速皮膚皮表角質層修復,表明其具有皮膚屏障修復功能;可以快速緩解由組胺引起皮膚瘙癢,顯著緩解由皮膚過敏引起的刺痛感,動物實驗已證實其止癢效果。 Pan M , Liu H T , Peng W , et al. Chitosan oligosaccharides inhibit LPS-induced over-expression of IL-6 and TNF-α in RAW264.7 macrophage cells through blockade of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling pathways - ScienceDirect[J]. Carbohydrate Polymers, 2011, 84(4):1391-1398. Minagawa T , Okamura Y , Shigemasa Y , et al. Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing[J]. Carbohydrate Polymers, 2007, 67(4):640-644.